MyBioSource.com's MEPCE Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot. The MEPCE Antibody was generated using MEPCE as the antigen and it reacts with Human, Mouse, Rat, and Zebrafish/Fish.
Description
Function: S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.
Subunit Structure: Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, MEPCE/BCDIN3, SART3 proteins and 7SK and U6 snRNAs (PubMed:17643375, Ref. 23). Interacts with METTL16 (PubMed:29051200).
Similarity: Belongs to the methyltransferase superfamily